Functional Testing

To order this report, you must have completed a DNA test kit with results dated within the last 6 months. If you do not have recent DNA test results, you can order a DNA Test Kit with this report here.

The Apolipoprotein E (APOE) gene is best known for its role in lipid (fat) metabolism by helping to remove cholesterol from the bloodstream. It can exist in three main forms known as E2, E3 and E4.

The E4 form of the APOE gene has been associated with increased plasma cholesterol and triglycerides and susceptibility to cardiovascular disease - heart attacks or strokes due to atherosclerosis, insulin resistance and Alzheimer’s disease. However, having an E4 genotype is one of many risk factors and does not mean you will develop any of these conditions.

In addition to APOE, this test examines genes involved in methylation, inflammation, toxicity and neuroprotection, to enable individuals to take preventative action by adopting personalised nutrition and lifestyle changes to optimise their future, long term health.

GI Effects is an innovative stool test measuring premier biomarkers of gastrointestinal function, providing valuable clinical insight into digestive performance, gut inflammation, and the gut microbiome — areas affecting not only GI health, but overall health as well.

Functional testing can help uncover the root cause of many chronic conditions that often frustrate both physician and patient. The scope of the biomarkers on the GI Effects Stool Profile provides comprehensive information to the clinician for the development of strategic interventions. As identified functional imbalances and inadequacies become more normalized through targeted dietary, lifestyle, and supplementation therapeutics, intractable symptoms often improve for many patients.

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Features

• Quick overview and synthesis of results reflecting the status of the 3 key functions of gut health in the “DIG” format:
  • Digestion
  • Inflammation
  • Gut microbiome
• Functional imbalance scores incorporating biomarkers from 5 functional categories:
  • Maldigestion
  • Inflammation
  • Dysbiosis
  • Metabolic imbalance
  • Infection
• Therapeutic support options to provide potential treatment ideas.
• Commensal Balance Infographic for precise analysis of commensal bacteria (PCR) results:
  • Total and relative comparisons to healthy and unhealthy commensal patterns.
  • Includes:
    • Inflammation-Associated Dysbiosis Score
    • Methane Dysbiosis Score (Immune Suppression)
• Clinical Association Charts to compare patient results with patterns observed in specific clinical conditions:
  • IBS
  • IBD
  • Metabolic Syndrome
  • Chronic Fatigue
  • Autoimmune dysfunction
  • Type 2 Diabetes
  • High Blood Pressure
  • Mood Disorders

Correlations are now evident between many disease processes and patterns of microbiome dysbiosis in both gut dysfunction and extra-intestinal disorders.